Rabbit Anti-Human BTK pAb
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产品编号
PA6379
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别名
AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA, BTK
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规格
- 50ul
- 100ul
| Catalog Number | PA6379 |
| Alias | AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA, BTK |
| Size | 50ul, 100ul |
| Product Full Name | Rabbit Anti-Human BTK Polyclonal Antibody |
| Molecular Name | BTK |
| Host | Rabbit |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Shipping Condition | Shipped on ice packs. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 173-272 of human BTK (NP_000052.1). |
| Application | WB, IHC |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
BTK(布鲁顿酪氨酸激酶)是B细胞受体信号核心分子,其突变导致X-连锁无丙种球蛋白血症(XLA),并作为B细胞淋巴瘤治疗靶点。
可以,推荐使用BTK抑制剂(如Ibrutinib)处理的B细胞淋巴瘤细胞,通过磷酸化流式检测PLCγ2活性抑制。
经测试无交叉反应,特异性针对BTK。
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