Rabbit Anti-Human ABCC5 pAb
-
产品编号
PA5706
-
别名
ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11
-
规格
- 50ul
- 100ul
Alias | ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 |
Catalog Number | PA5706 |
Molecular Name | ABCC5 |
Host | Rabbit |
Size | 50ul, 100ul |
Clonity | Polyclonal |
Purification | Affinity Purification |
Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
Immunogen | A synthetic peptide corresponding to a sequence within a.a. 1-100 of human ABCC5 (NP_005679.2). |
Application | WB, IHC |
Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
Shipping Condition | Shipped on ice packs. |
Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
Product Full Name | Rabbit Anti-Human ABCC5 Polyclonal Antibody |
ABCC5(MRP5)属于ABC转运蛋白家族,介导核苷类似物(如抗癌药物吉西他滨)和环核苷酸(cGMP/cAMP)的外排,与肿瘤耐药性及神经系统信号调控相关。
是的,推荐用于耐药细胞系(如HCT-15)的Western Blot(WB)和免疫荧光(IF),建议结合药物处理验证功能。
与人ABCC5序列同源性约80%(小鼠),需通过预实验验证交叉反应性(推荐起始稀释1:500)。
理论分子量约160 kDa,实际可能因糖基化显示为~180 kDa条带。
建议高压热修复抗原(pH 9.0 Tris-EDTA缓冲液),并使用HRP-聚合物增强系统降低背景。