Rabbit Anti-Human SHARPIN pAb
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产品编号
PA5601
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别名
SHARPIN, SIPL1, sharpin
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规格
- 50ul
- 100ul
| Catalog Number | PA5601 |
| Alias | SHARPIN, SIPL1, sharpin |
| Size | 50ul, 100ul |
| Product Full Name | Rabbit Anti-Human SHARPIN Polyclonal Antibody |
| Molecular Name | SHARPIN |
| Host | Rabbit |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Shipping Condition | Shipped on ice packs. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 1-170 of human SHARPIN (NP_112236.3). |
| Application | WB |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
SHARPIN(线性泛素链复合体LUBAC组分)调控NF-κB信号通路及细胞凋亡抑制,其突变导致慢性炎症(如慢性增殖性皮炎)和免疫失调。
可以,推荐使用SHARPIN敲除小鼠模型,检测皮肤炎症反应及IL-1β分泌异常。
经测试无交叉反应,特异性针对SHARPIN。
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