Rabbit Anti-Human SMAD6 pAb
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产品编号
PA4441
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别名
SMAD6, AOVD2, HsT17432, MADH6, MADH7
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规格
- 50ul
- 100ul
| Catalog Number | PA4441 |
| Alias | SMAD6, AOVD2, HsT17432, MADH6, MADH7 |
| Size | 50ul, 100ul |
| Product Full Name | Rabbit Anti-Human SMAD6 Polyclonal Antibody |
| Molecular Name | SMAD6 |
| Host | Rabbit |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Shipping Condition | Shipped on ice packs. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 257-496 of human Smad6 (NP_005576.3). |
| Application | WB |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
SMAD6是抑制型SMAD蛋白,负调控BMP信号通路,通过竞争性结合BMP受体或招募泛素连接酶降解SMAD1/5/9,参与心血管发育及骨代谢。其异常与肺动脉高压及骨形成异常相关。
可以,推荐使用BMP信号激活的内皮细胞模型,检测SMAD6过表达后的血管平滑肌增生抑制。
经测试无交叉反应,特异性针对SMAD6。
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