Rabbit Anti-Human SIRT1 pAb
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产品编号
PA4297
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别名
SIR2, SIR2L1, SIR2alpha, SIRT1, sirtuin 1
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规格
- 50ul
- 100ul
| Catalog Number | PA4297 |
| Alias | SIR2, SIR2L1, SIR2alpha, SIRT1, sirtuin 1 |
| Size | 50ul, 100ul |
| Product Full Name | Rabbit Anti-Human SIRT1 Polyclonal Antibody |
| Molecular Name | SIRT1 |
| Host | Rabbit |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Shipping Condition | Shipped on ice packs. |
| Immunogen | A synthetic peptide of human SIRT1 |
| Application | WB, IF |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
SIRT1是NAD⁺依赖的去乙酰化酶,调控衰老、代谢及DNA修复,通过激活AMPK/PGC-1α通路改善胰岛素敏感性,其表达异常与糖尿病、神经退行性相关。
可以,推荐使用高脂饮食小鼠模型,检测肝脏脂质代谢及线粒体功能改善(如通过Resveratrol激活SIRT1)。
经测试无交叉反应,特异性针对SIRT1。
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