Rabbit Anti-Human BRCA1 pAb
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产品编号
PA4280
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别名
BRCA1, BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53
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规格
- 50ul
- 100ul
Alias | BRCA1, BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53 |
Catalog Number | PA4280 |
Molecular Name | BRCA1 |
Host | Rabbit |
Size | 50ul, 100ul |
Clonity | Polyclonal |
Purification | Affinity Purification |
Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
Immunogen | A synthetic peptide corresponding to a sequence within a.a. 120-220 of human BRCA1 (NP_009225.1). |
Application | WB, IHC, IF |
Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
Shipping Condition | Shipped on ice packs. |
Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
Product Full Name | Rabbit Anti-Human BRCA1 Polyclonal Antibody |
BRCA1是DNA同源重组修复关键蛋白,其胚系突变显著增加乳腺癌、卵巢癌及前列腺癌风险,并影响PARP抑制剂疗效。
可以,推荐使用BRCA1突变患者来源的类器官或PDX模型,通过彗星实验检测DNA损伤累积。
经测试无交叉反应,特异性针对BRCA1。