Rabbit Anti-Human APP pAb
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产品编号
PA4274
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别名
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4, APP, Aβ42, preA4
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规格
- 50ul
- 100ul
| Catalog Number | PA4274 |
| Alias | AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4, APP, Aβ42, preA4 |
| Size | 50ul, 100ul |
| Product Full Name | Rabbit Anti-Human APP Polyclonal Antibody |
| Molecular Name | APP |
| Host | Rabbit |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Shipping Condition | Shipped on ice packs. |
| Immunogen | A synthetic peptide corresponding to a sequence within a.a. 190-290 of human APP (NP_000475.1). |
| Application | WB, IHC |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
APP(淀粉样前体蛋白)经β-和γ-分泌酶切割生成β-淀粉样蛋白(Aβ),其异常积累是阿尔茨海默病(AD)的核心特征,与神经元死亡及淀粉样斑块形成直接相关。
可以,推荐使用APP/PS1转基因小鼠脑组织或Aβ处理的神经元模型,通过IHC或WB检测APP剪切产物(如Aβ42)。
经测试无交叉反应,特异性针对人源APP。
使用Tris-Tricine凝胶分离小分子量Aβ(4-20 kDa),或检测全长APP(约110 kDa)。
分装后-20℃保存,稀释后4℃保存不超过1周,有效期2年。
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