Rabbit Anti Human KLK4 Polyclonal Antibody_天津卡梅德科技发展有限公司

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Rabbit Anti Human KLK4 Polyclonal Antibody

Rabbit Anti Human KLK4 Polyclonal Antibody

产品编号

PA17209

别名

Anti KLK4 Antibody, Rabbit anti Human KLK4 pAb, Rabbit anti Human Kallikrein 4 Polyclonal Antibody, Anti KLK4 Antibody Rabbit Polyclonal

规格

100ul

DATASHEET MSDS

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产品介绍

Alias	Anti KLK4 Antibody, Rabbit anti Human KLK4 pAb, Rabbit anti Human Kallikrein 4 Polyclonal Antibody, Anti KLK4 Antibody Rabbit Polyclonal
Catalog Number	PA17209
Product Description	The Rabbit Anti Human KLK4 Polyclonal Antibody was obtained by affinity purification from a rabbit immunized with purified recombinant Human KLK4 protein.
Molecular Name	KLK4, Kallikrein 4
Host	Rabbit
Size	100ul
Clonity	Polyclonal
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Formulation	PBS, pH7.4
Background	Kallikrein 4, also known as Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK L1, Serine protease 17, KLK4, PRSS17, and EMSP1, is a secreted protein that belongs to the peptidase S1 family and Kallikrein subfamily. Kallikrein-4 / KLK4 is a serine protease expressed during enamel maturation, and proteolytic processing of the enamel matrix by KLK4 is critical for proper enamel formation. Kallikrein-4 / KLK4 contains one peptidase S1 domain. Kallikrein-4 / KLK4 is secreted by transition- and maturation-stage ameloblasts. KLK4 aggressively degrades the retained organic matrix following the termination of enamel protein secretion. Two proteases are secreted into the enamel matrix of developing teeth. The early protease is enamelysin (MMP-2). The late protease is kallikrein 4 (KLK4). The principal functions of MMP-2 and KLK4 in dental enamel formation are to facilitate the orderly replacement of organic matrix with mineral, generating an enamel layer that is harder, less porous, and unstained by retained enamel proteins. Defects in Kallikrein-4/KLK4 are the cause of Amelogenesis Imperfecta Hypomaturation type 2A1 (AI2A1) which is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions.
Immunogen	Recombinant Human KLK4 Protein(Met1-Ser254)
Application	ELISA
Storage Condition	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Condition	This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Cross-reactivity	No cross-reactivity with other antigens or proteins.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。

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