Rabbit anti-C Peptide (mouse) Polyclonal antibody
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产品编号
MA1579
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别名
proinsulin precursor,Proinsulin,Propeptide,C-Peptide
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规格
- 50ul
- 100ul
- 200ul
产品介绍
| Alias | proinsulin precursor,Proinsulin,Propeptide,C-Peptide |
| Catalog Number | MA1579 |
| Molecular Name | C Peptide |
| Host | Rabbit |
| Size | 50ul,100ul,200ul |
| Clonity | Polyclonal |
| Concentration | 1mg/ml |
| Purification | affinity purified by Protein A |
| Formulation | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Background | C Peptide is part of the molecule of Proinsulin, that consists of three parts: C Peptide and two long strands of amino acids (called the alpha and beta chains) that later become linked together to form the insulin molecule. From every molecule of proinsulin, one molecule of insulin plus one molecule of C Peptide are produced. C peptide is released into the blood stream in equal amounts to insulin. A test of C peptide levels will show how much insulin the body is making. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
| Immunogen | KLH conjugated synthetic peptide derived from mouse C Peptide: 57-87/110 |
| Application | IHC-P, IHC-F,ICC,IF |
| Storage Condition | Shipped at 4℃. Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles |
| Cross-reactivity | Rat, (predicted: Mouse ) |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
FAQ
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Q1-C肽抗体的主要应用是什么？
C肽是胰岛素原分解产物，用于评估胰岛β细胞功能。该抗体适用于糖尿病研究，通过ELISA或IHC检测小鼠胰岛中C肽分泌水平。
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Q2-是否适用于1型糖尿病模型？
可以，推荐使用链脲佐菌素（STZ）诱导的糖尿病小鼠，检测胰腺中C肽表达降低。
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Q3-是否与胰岛素或胰高血糖素交叉反应？
经测试无交叉反应，特异性针对C肽。
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