Rabbit Anti-VEGFA antibody_天津卡梅德科技发展有限公司

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Rabbit Anti-VEGFA antibody

Rabbit Anti-VEGFA antibody

产品编号

MA1575

别名

VEGF A,VEGF-A,VEGF

规格

50ul
100ul
200ul

DATASHEET MSDS

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产品介绍

Alias	VEGF A,VEGF-A,VEGF
Catalog Number	MA1575
Product Description	This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Molecular Name	VEGF-A
Host	Rabbit
Size	50ul,100ul,200ul
Clonity	Polyclonal
Concentration	1mg/ml
Purification	affinity purification
Formulation	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background	This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Immunogen	KLH conjugated synthetic peptide derived from human VEGFA: 301-393/393
Application	WB, ELISA, IHC-P, IHC-F, IF
Cross-reactivity	Mouse, Rat, Guinea Pig, (predicted: Human, Chicken, Dog, Pig, Cow, Sheep, )
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。

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