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Rabbit Anti-HIF-1 Alpha antibody

Rabbit Anti-HIF-1 Alpha antibody

产品编号

MA1574

别名

PASD 8,PASD8,HIF-1a,HIF-1α

规格
  • 50ul
  • 100ul
  • 200ul
产品介绍
AliasPASD 8,PASD8,HIF-1a,HIF-1α
Catalog NumberMA1574
Product DescriptionHypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator(ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.
Molecular NameHIF-1α
HostRabbit
Size50ul,100ul,200ul
ClonityPolyclonal
Concentration1mg/ml
Purificationaffinity purification
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
BackgroundHypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator(ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.
ImmunogenKLH conjugated synthetic peptide derived from middle of human HIF-1 Alpha: 341-450/826
ApplicationWB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF
Cross-reactivityHuman, Rat, (predicted: Mouse, Dog, Pig, Cow, Rabbit, )
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。

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