Rabbit Anti-HIF-1 Alpha antibody
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产品编号
MA1574
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别名
PASD 8,PASD8,HIF-1a,HIF-1α
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规格
- 50ul
- 100ul
- 200ul
Alias | PASD 8,PASD8,HIF-1a,HIF-1α |
Catalog Number | MA1574 |
Product Description | Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator(ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. |
Molecular Name | HIF-1α |
Host | Rabbit |
Size | 50ul,100ul,200ul |
Clonity | Polyclonal |
Concentration | 1mg/ml |
Purification | affinity purification |
Formulation | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Background | Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator(ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. |
Immunogen | KLH conjugated synthetic peptide derived from middle of human HIF-1 Alpha: 341-450/826 |
Application | WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF |
Cross-reactivity | Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Rabbit, ) |
Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |