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Rabbit Anti Human BNP Polyclonal Antibody

Rabbit Anti Human BNP Polyclonal Antibody

产品编号

PA12838

别名

BNP antibody, BNP polyclonal antibody, BNP Rabbit pAb, BNP, Iso-ANP

规格
  • 50ul
  • 100ul
  • 200ul
产品介绍
AliasBNP antibody, BNP polyclonal antibody, BNP Rabbit pAb, BNP, Iso-ANP
Catalog NumberPA12838
ClonityPolyclonal
Size50ul, 100ul, 200ul
Product DescriptionThe Rabbit Anti Human BNP Polyclonal Antibody was obtained by affinity purification from a rabbit immunized with a purified synthetic peptide corresponding to a sequence within amino acids 35-134 of human BNP (NP_002512.1)
Storage ConditionStore at -20℃. Avoid freeze / thaw cycles.
FormulationBuffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Shipping ConditionThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
BackgroundThis gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
HostRabbit
PurificationAffinity purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 35-134 of human BNP (NP_002512.1)
Stabilitystable at -20 ° C
Cross-reactivityHuman, Mouse, Rat
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
FAQ
  • Q1- 是否用于心力衰竭诊断?

    是,检测血浆B型利钠肽(BNP),ELISA灵敏度0.5 pg/mL,符合CLIA标准。

  • Q2- 是否与ANP(心房利钠肽)交叉反应?

    交叉反应率<0.1%,确保BNP特异性检测。

  • Q3- 样本类型及处理?

    EDTA抗凝血浆,4℃离心(3000 rpm,10分钟)去除血小板。

  • Q4- 是否支持化学发光法?

    是,检测限0.1 pg/mL,动态范围1-5000 pg/mL(适配Roche Cobas平台)。

  • Q5- 保存条件?

    冻干粉-80℃保存3年,复溶后4℃保存1周(含0.1% BSA)。

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