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Rabbit Anti-CO5/C5 Polyclonal Antibody

Rabbit Anti-CO5/C5 Polyclonal Antibody

产品编号

PAV946

别名

complement C5, C5D, C5a, C5b, CPAMD4, ECLZB

规格
  • 100ul
产品介绍
Aliascomplement C5, C5D, C5a, C5b, CPAMD4, ECLZB
Catalog NumberPAV946
Molecular NameC5 
HostRabbit
Size100ul
ClonityPolyclonal
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
ImmunogenThis antibody was raised against from human protein at amino acid: 690-770
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
FAQ
  • Q1-C5的生物学功能是什么?

    C5是补体系统的核心成分,裂解生成C5a(趋化因子)和C5b(MAC起始因子),介导炎症及病原体溶解,其靶向药物(如Eculizumab)用于治疗阵发性睡眠性血红蛋白尿症(PNH)。

  • Q2-是否适用于补体抑制剂研究?

    可以,推荐使用Eculizumab处理的样本,通过ELISA检测C5活性抑制效果。

  • Q3-是否与C3或C6交叉反应?

    经测试无交叉反应,特异性针对C5。

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