Rabbit Anti-Human AMOT pAb
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产品编号
PA16285
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别名
AMOT
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规格
- 50ul
- 100ul
Alias | AMOT |
Catalog Number | PA16285 |
Molecular Name | AMOT |
Host | Rabbit |
Size | 50ul, 100ul |
Clonity | Polyclonal |
Purification | Affinity Purification |
Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 1-300 of human AMOT (NP_573572.1). |
Application | WB, IHC |
Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
Shipping Condition | Shipped on ice packs. |
Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
Product Full Name | Rabbit Anti-Human AMOT Polyclonal Antibody |
AMOT(血管生成抑制蛋白)通过Hippo信号通路抑制YAP/TAZ活性,调控血管生成及肿瘤转移,在乳腺癌、肝癌中发挥抑癌作用。
可以,结合Transwell实验或3D肿瘤球体模型,检测AMOT敲低后细胞侵袭能力增强。
此抗体特异性识别总AMOT(全长及剪切亚型),不与其他AMOT家族成员(AMOTL1/L2)交叉反应。
使用抗YAP抗体共染色,透膜条件为0.1% Triton X-100处理10分钟,固定剂为4%多聚甲醛。
WB建议1:1000,IF建议1:200;分装后-20℃保存,有效期2年;稀释后4℃保存不超过1周。