Rabbit Anti-Human ASPA pAb
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产品编号
PA15554
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别名
ASPA, ACY2, ASP
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规格
- 50ul
- 100ul
Alias | ASPA, ACY2, ASP |
Catalog Number | PA15554 |
Molecular Name | ASPA |
Host | Rabbit |
Size | 50ul, 100ul |
Clonity | Polyclonal |
Purification | Affinity Purification |
Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 1-313 of human ASPA (NP_001121557.1). |
Application | WB, IF |
Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
Shipping Condition | Shipped on ice packs. |
Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
Product Full Name | Rabbit Anti-Human ASPA Polyclonal Antibody |
ASPA(天冬氨酸酰化酶)催化神经代谢物N-乙酰天冬氨酸(NAA)水解为天冬氨酸和乙酸,对中枢神经系统髓鞘的形成和维持至关重要。其活性缺失会导致NAA积累,引发卡纳万病(Canavan disease),一种致命性脑白质营养不良症。
可以,推荐使用卡纳万病患者脑组织或ASPA敲除动物模型,通过WB或IHC检测ASPA表达缺失及NAA水平升高。
经测试无交叉反应,特异性针对人源ASPA,不识别其他代谢酶类。
使用含1% Triton X-100的裂解液提取脑组织蛋白,避免过度超声以减少髓鞘脂蛋白干扰。
分装后-20℃保存,避免反复冻融;WB建议1:1000稀释,IHC建议1:200,有效期2年。