Rabbit Anti-Human BRD4-L Polyclonal Antibody
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产品编号
PA12154
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别名
BRD4, CAP, HUNK1, HUNKI, MCAP
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规格
- 50ul
- 100ul
| Catalog Number | PA12154 |
| Alias | BRD4, CAP, HUNK1, HUNKI, MCAP |
| Size | 50ul, 100ul |
| Molecular Name | BRD4-L |
| Host | Rabbit |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Shipping Condition | Shipped on ice packs. |
| Immunogen | A synthetic peptide corresponding to a sequence within a.a. 700-800 of human BRD4-L (NP_490597.1). |
| Application | WB |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
BRD4长异构体(BRD4-L)作为表观遗传阅读器,通过结合乙酰化组蛋白驱动致癌基因(如MYC)转录,其异常与白血病及实体瘤靶向治疗耐药相关。
可以,推荐使用JQ1处理的癌细胞,通过qPCR检测MYC表达下调。
该抗体特异性针对BRD4-L,不识别BRD4-S。
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