Rabbit Anti-Human BTRC pAb
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产品编号
PA10263
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别名
BTRC, BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, bTrCP, bTrCP1, betaTrCP, Beta-TRCP
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规格
- 50ul
- 100ul
Alias | BTRC, BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, bTrCP, bTrCP1, betaTrCP, Beta-TRCP |
Catalog Number | PA10263 |
Molecular Name | BTRC |
Host | Rabbit |
Size | 50ul, 100ul |
Clonity | Polyclonal |
Purification | Affinity Purification |
Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 50-340 of human Beta-TRCP (NP_378663.1). |
Application | WB, IHC, IF |
Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
Shipping Condition | Shipped on ice packs. |
Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
Product Full Name | Rabbit Anti-Human BTRC Polyclonal Antibody |
BTRC(β-TrCP)是E3泛素连接酶,介导IκB、β-catenin等蛋白降解,其异常导致Wnt/NF-κB信号失调,与炎症性肠病及肝癌相关。
可以,推荐使用TOP/FOP荧光素酶报告系统,检测BTRC敲除后β-catenin活性升高。
经测试无交叉反应,特异性针对BTRC。