Pneumococcal Type 19A Antigen, CRM197-Conjugate
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产品编号
BAG1141
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别名
CRM197结合19A型肺炎球菌抗原,CRM197结合肺炎球菌抗原, 肺炎球菌, Pneumococcal Type 19A, CRM197
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规格
- 250ul
- 1ml
| Catalog Number | BAG1141 |
| Alias | CRM197结合19A型肺炎球菌抗原,CRM197结合肺炎球菌抗原, 肺炎球菌, Pneumococcal Type 19A, CRM197 |
| Size | 250ul, 1ml |
| Molecular Name | Pneumococcal |
| Expression System | Pneumococcal |
| Species | Bacteria |
| Purity | >95% |
| Purification | IEC & HPLC |
| Storage Condition | Store the lyophilized powder at 4℃ for 6 months. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Formulation | Powder or 0.1M PBS, PH 7.0 |
| Background | In most cases, once pneumococcal pneumonia has been identified, doctors will prescribe antibiotics. These antibiotic usually help alleviate and eliminate symptoms between 12 and 36 hours after being taken. Despite most antibiotics' effectiveness in treating the disease, sometimes the bacteria can resist the antibiotics, causing symptoms to worsen. Additionally, age and health of the infected patient can contribute to the effectiveness of the antibiotics. |
| Application | Immunogen, WB, ELISA |
作为疫苗的关键原物料,其质量控制极其严格,主要包括: 鉴别试验: 确认是目标血清型多糖与CRM197的正确结合物。 多糖含量与蛋白含量: 确保有效成分的准确剂量。 游离多糖含量: 必须控制在极低水平,未结合的多糖不能提供T细胞依赖性免疫。 分子大小分布: 通常使用尺寸排阻色谱监测,大小与免疫原性相关。 无菌试验、内毒素检测: 确保安全性。 免疫原性评估: 在动物模型(如小鼠)中测试其诱发特异性抗体(针对多糖)的能力。
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