Inactivated Pneumococcal Type 33F Antigen
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产品编号
BAG1129
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别名
灭活33F型肺炎球菌抗原,灭活肺炎球菌抗原, 肺炎球菌, Inactivated Pneumococcal Type 33F, Pneumococcal
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规格
- 250ul
- 1ml
| Catalog Number | BAG1129 |
| Alias | 灭活33F型肺炎球菌抗原,灭活肺炎球菌抗原, 肺炎球菌, Inactivated Pneumococcal Type 33F, Pneumococcal |
| Size | 250ul, 1ml |
| Molecular Name | Pneumococcal |
| Expression System | Pneumococcal |
| Species | Bacteria |
| Purity | >95% |
| Purification | IEC & HPLC |
| Storage Condition | Store the lyophilized powder at 4℃ for 6 months. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Formulation | Powder or 0.1M PBS, PH 7.0 |
| Background | The symptoms of pneumococcal pneumonia can occur suddenly, typically presenting as a severe chill, later including a severe fever, cough, shortness of breath, rapid breathing, and chest pains. Other symptoms like nausea, vomiting, headache, fatigue, and muscle aches could also accompany the original symptoms. Sometimes the coughing can produce rusty or blood-streaked sputum. In 25% of cases, a parapneumonic effusion may occur. Chest X-rays will typically show lobar consolidation or patchy infiltrates. |
| Application | Immunogen, WB, ELISA |
作为疫苗的关键原物料,其质量控制极其严格,主要包括: 鉴别试验: 确认是目标血清型多糖与CRM197的正确结合物。 多糖含量与蛋白含量: 确保有效成分的准确剂量。 游离多糖含量: 必须控制在极低水平,未结合的多糖不能提供T细胞依赖性免疫。 分子大小分布: 通常使用尺寸排阻色谱监测,大小与免疫原性相关。 无菌试验、内毒素检测: 确保安全性。 免疫原性评估: 在动物模型(如小鼠)中测试其诱发特异性抗体(针对多糖)的能力。
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