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Streptococcus Pyogenes IdeS Protein, His Tag

Streptococcus Pyogenes IdeS Protein, His Tag

产品编号

KMP4414

别名

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Catalog NumberKMP4414
Molecular NameIdeS
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
Product DescriptionThe Streptococcus Pyogenes IdeS Protein, His Tag(KMP4414) is produced in E. coli. A DNA sequence encoding the streptococcus pyogenes IdeS (F8V4V0-1) (Asp30-Asn341) was expressed with a polyhistidine tag at the N-terminus.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
FormulationPBS, 50% Glycerol, pH6.6
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
BackgroundIdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic cleavage at the lower hinge of human IgG. This proteolytic degradation promotes inhibition of opsonophagocytosis and interferes with the killing of group A Streptococcus.
SpeciesStreptococcus Pyogenes
HostE. coli
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method

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