Rabbit Anti-MAGD2/MAGED2 Polyclonal Antibody
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产品编号
PAV2225
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别名
MAGE family member D2, 11B6, BARTS5, BCG-1, BCG1, HCA10, MAGE-D2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | MAGE family member D2, 11B6, BARTS5, BCG-1, BCG1, HCA10, MAGE-D2 |
| Catalog Number | PAV2225 |
| Product Description | Rabbit polyclonal antibody raised against human MAGED2 (Melanoma-associated antigen D2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MAGED2 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 肿瘤标志物 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked intellectual disability (XLID). Mutations in this gene cause a form of transient antenatal Bartter's syndrome. This gene may also be involved in several types of cancer, including breast cancer and melanoma. The protein encoded by this gene is progressively recruited from the cytoplasm to the nucleoplasm during the interphase and after nucleolar stress and is thus thought to play a role in cell cycle regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017] |
| Immunogen | This antibody was raised against from part region of human MAGED2 protein (UniProt: Q9UNF1) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 10916 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈65.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 65.0 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9UNF1 |
| Note | Gene ID: 10916; UniProt: Q9UNF1; Chromosome: Xp11.21; Predicted MW: 65.0 kDa |
| Function | Regulates the expression, localization to the plasma membrane and function of the sodium chloride cotransporters SLC12A1 and SLC12A3, two key components of salt reabsorption in the distal renal tubule. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MAGED2 Polyclonal Antibody |
| Target | MAGED2 |
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