Rabbit Anti-SO4C1/SLCO4C1 Polyclonal Antibody
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产品编号
PAV3742
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别名
solute carrier organic anion transporter family member 4C1, OATP-H, OATP-M1, OATP4C1, OATPX, PRO2176, SLC21A20
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | solute carrier organic anion transporter family member 4C1, OATP-H, OATP-M1, OATP4C1, OATPX, PRO2176, SLC21A20 |
| Catalog Number | PAV3742 |
| Product Description | Rabbit polyclonal antibody raised against human SLCO4C1 (Solute carrier organic anion transporter family member 4C1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SLCO4C1 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转运蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | SLCO4C1 belongs to the organic anion transporter (OATP) family. OATPs are involved in the membrane transport of bile acids, conjugated steroids, thyroid hormone, eicosanoids, peptides, and numerous drugs in many tissues (Mikkaichi et al., 2004 [PubMed 14993604]).[supplied by OMIM, Mar 2008] |
| Immunogen | This antibody was raised against from part region of human SLCO4C1 protein (UniProt: Q6ZQN7) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 353189 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈78.9 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 78.9 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q6ZQN7 |
| Note | Gene ID: 353189; UniProt: Q6ZQN7; Chromosome: 5q21.1; Predicted MW: 78.9 kDa |
| Function | Mediates the transport of organic anions such as steroids (estrone 3-sulfate, chenodeoxycholate, glycocholate) and thyroid hormones (3,3',5-triiodo-L-thyronine (T3), L-thyroxine (T4)), in the kidney. Capable of transporting cAMP and pharmacological substances such as digoxin, ouabain and methotrexate. Transport is independent of sodium, chloride ion, and ATP. Transport activity is stimulated by an acidic extracellular environment due to increased substrate affinity to the transporter. The driving force for this transport activity is currently not known (By similarity). The role of hydrogencarbonate (HCO3(-), bicarbonate) as the probable counteranion that exchanges for organic anions is still not well defined. Functions as an uptake transporter at the apical membrane, suggesting a role in renal reabsorption (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SLCO4C1 Polyclonal Antibody |
| Target | SLCO4C1 |
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