Rabbit Anti-SC5AC/SLC5A12 Polyclonal Antibody
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产品编号
PAV3584
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别名
solute carrier family 5 member 12, SMCT2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | solute carrier family 5 member 12, SMCT2 |
| Catalog Number | PAV3584 |
| Product Description | Rabbit polyclonal antibody raised against human SLC5A12 (Sodium-coupled monocarboxylate transporter 2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SLC5A12 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转运蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).[supplied by OMIM, Dec 2008] |
| Immunogen | This antibody was raised against from part region of human SLC5A12 protein (UniProt: Q1EHB4) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 159963 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈67.6 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 67.6 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q1EHB4 |
| Note | Gene ID: 159963; UniProt: Q1EHB4; Chromosome: 11p14.2; Predicted MW: 67.6 kDa |
| Function | Acts as an electroneutral and low-affinity sodium Na(+)-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate (By similarity). May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina (By similarity). Probably part of D-serine transport systems involved in D-serine reabsorption at the brush border of renal proximal tubules. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SLC5A12 Polyclonal Antibody |
| Target | SLC5A12 |
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