Rabbit Anti-S7A14/SLC7A14 Polyclonal Antibody
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产品编号
PAV3563
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别名
solute carrier family 7 member 14, PPP1R142
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | solute carrier family 7 member 14, PPP1R142 |
| Catalog Number | PAV3563 |
| Product Description | Rabbit polyclonal antibody raised against human SLC7A14 (Solute carrier family 7 member 14). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SLC7A14 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转运蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014] |
| Immunogen | This antibody was raised against from part region of human SLC7A14 protein (UniProt: Q8TBB6) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 57709 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈84.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 84.1 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q8TBB6 |
| Note | Gene ID: 57709; UniProt: Q8TBB6; Chromosome: 3q26.2; Predicted MW: 84.1 kDa |
| Function | Imports 4-aminobutanoate (GABA) into lysosomes. May act as a GABA sensor that regulates mTORC2-dependent INS signaling and gluconeogenesis. The transport mechanism and substrate selectivity remain to be elucidated. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SLC7A14 Polyclonal Antibody |
| Target | SLC7A14 |
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