Rabbit Anti-S39A5/SLC39A5 Polyclonal Antibody
-
产品编号
PAV3547
-
别名
solute carrier family 39 member 5, LZT-Hs7, MYP24, ZIP5
-
目录价格
InquiryRMB
-
规格
- 100ul
产品介绍
| Alias | solute carrier family 39 member 5, LZT-Hs7, MYP24, ZIP5 |
| Catalog Number | PAV3547 |
| Product Description | Rabbit polyclonal antibody raised against human SLC39A5 (Zinc transporter ZIP5). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SLC39A5 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转运蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014] |
| Immunogen | This antibody was raised against from part region of human SLC39A5 protein (UniProt: Q6ZMH5) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 283375 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈56.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 56.5 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q6ZMH5 |
| Note | Gene ID: 283375; UniProt: Q6ZMH5; Chromosome: 12q13.3; Predicted MW: 56.5 kDa |
| Function | Uniporter that transports zinc(2+) into polarized cells of enterocytes, pancreatic acinar and endoderm cells across the basolateral membrane and participates, notably, in zinc excretion from the intestine by the uptake of zinc from the blood into the intestine (By similarity). The transport mechanism is temperature- and concentration-dependent and saturable (By similarity). In addition, is also a high affinity copper transporter in vitro. Also may regulate glucose-stimulated insulin secretion (GSIS) in islets primarily through the zinc-activated SIRT1-PPARGC1A axis (By similarity). Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera. Plays a role in eye development. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SLC39A5 Polyclonal Antibody |
| Target | SLC39A5 |
- 联系我们
- 电话：400-621-6806
- 手机：13116038708（微信）
- 邮箱：info@kmdbioscience.com
- 地址：天津市武清开发区和畅路6号10号厂房108室
-
销售微信
-
官方公众号
-
400-621-6806 -
3599163699 -
周一至周五 9:00-18:00 -
-
0
-
