Rabbit Anti-S29A2/SLC29A2 Polyclonal Antibody
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产品编号
PAV3538
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别名
solute carrier family 29 member 2, DER12, ENT2, HNP36, hENT2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | solute carrier family 29 member 2, DER12, ENT2, HNP36, hENT2 |
| Catalog Number | PAV3538 |
| Product Description | Rabbit polyclonal antibody raised against human SLC29A2 (Equilibrative nucleoside transporter 2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SLC29A2 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转运蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008] |
| Immunogen | This antibody was raised against from part region of human SLC29A2 protein (UniProt: Q14542) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 3177 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈50.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 50.1 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q14542 |
| Note | Gene ID: 3177; UniProt: Q14542; Chromosome: 11q13.2; Predicted MW: 50.1 kDa |
| Function | Bidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent, passive transporter. Involved in the transport of nucleosides such as inosine, adenosine, uridine, thymidine, cytidine and guanosine. Also able to transport purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Also mediates nicotinamide uptake supporting homeostasis and modulating its biological activities. Can also transport urate. Involved in nucleoside transport at basolateral membrane of kidney cells, allowing liver absorption of nucleoside metabolites. Mediates apical nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis-barrier. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SLC29A2 Polyclonal Antibody |
| Target | SLC29A2 |
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