Rabbit Anti-TCF25 Polyclonal Antibody
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产品编号
PAV3987
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别名
TCF25 ribosome quality control complex subunit, FKSG26, Hulp1, NULP1, PRO2620, hKIAA1049
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | TCF25 ribosome quality control complex subunit, FKSG26, Hulp1, NULP1, PRO2620, hKIAA1049 |
| Catalog Number | PAV3987 |
| Product Description | Rabbit polyclonal antibody raised against human TCF25 (Ribosome quality control complex subunit TCF25). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TCF25 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 翻译与核糖体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM, Sep 2008] |
| Immunogen | This antibody was raised against from part region of human TCF25 protein (UniProt: Q9BQ70) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 22980 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈76.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 76.7 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9BQ70 |
| Note | Gene ID: 22980; UniProt: Q9BQ70; Chromosome: 16q24.3; Predicted MW: 76.7 kDa |
| Function | Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. In the RQC complex, required to promote formation of 'Lys-48'-linked polyubiquitin chains during ubiquitination of incompletely synthesized proteins by LTN1. May negatively regulate the calcineurin-NFAT signaling cascade by suppressing the activity of transcription factor NFATC4 (By similarity). May play a role in cell death control (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TCF25 Polyclonal Antibody |
| Target | TCF25 |
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