Rabbit Anti-SYCM/CARS2 Polyclonal Antibody
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产品编号
PAV3887
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别名
cysteinyl-tRNA synthetase 2, mitochondrial, COXPD27, cysRS
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | cysteinyl-tRNA synthetase 2, mitochondrial, COXPD27, cysRS |
| Catalog Number | PAV3887 |
| Product Description | Rabbit polyclonal antibody raised against human CARS2 (Probable cysteine--tRNA ligase, mitochondrial). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | CARS2 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 翻译与核糖体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a putative member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of cysteine to tRNA molecules. A splice-site mutation in this gene has been associated with a novel progressive myoclonic epilepsy disease with similar symptoms to MERRF syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2017] |
| Immunogen | This antibody was raised against from part region of human CARS2 protein (UniProt: Q9HA77) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 79587 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈62.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 62.2 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9HA77 |
| Note | Gene ID: 79587; UniProt: Q9HA77; Chromosome: 13q34; Predicted MW: 62.2 kDa |
| Function | Mitochondrial cysteine-specific aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).; FUNCTION: In addition to its role as an aminoacyl-tRNA synthetase, has also cysteine persulfide synthase activity. Produces reactive persulfide species such as cysteine persulfide (CysSSH) from substrate cysteine and mediate direct incorporation of CysSSH into proteins during translations, resulting in protein persulfides and polysulfides. CysSSHs behave as potent antioxidants and cellular protectants. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human CARS2 Polyclonal Antibody |
| Target | CARS2 |
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