Rabbit Anti-RM27/MRPL27 Polyclonal Antibody
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产品编号
PAV3402
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别名
mitochondrial ribosomal protein L41, BMRP, MRP-L27, MRPL27, PIG3, RPML27, mL41
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | mitochondrial ribosomal protein L41, BMRP, MRP-L27, MRPL27, PIG3, RPML27, mL41 |
| Catalog Number | PAV3402 |
| Product Description | Rabbit polyclonal antibody raised against human MRPL41 (Large ribosomal subunit protein mL41). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MRPL41 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 翻译与核糖体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human MRPL41 protein (UniProt: Q8IXM3) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 64975 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈15.4 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 15.4 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q8IXM3 |
| Note | Gene ID: 64975; UniProt: Q8IXM3; Chromosome: 9q34.3; Predicted MW: 15.4 kDa |
| Function | Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MRPL41 Polyclonal Antibody |
| Target | MRPL41 |
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