Rabbit Anti-TLE1 Polyclonal Antibody
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产品编号
PAV4040
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别名
TLE family member 1, transcriptional corepressor, ESG, ESG1, GRG1, TLE-1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | TLE family member 1, transcriptional corepressor, ESG, ESG1, GRG1, TLE-1 |
| Catalog Number | PAV4040 |
| Product Description | Rabbit polyclonal antibody raised against human TLE1 (Transducin-like enhancer protein 1 homolog)). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TLE1 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables DNA-binding transcription factor binding activity; identical protein binding activity; and transcription corepressor activity. Involved in negative regulation of anoikis; negative regulation of signal transduction; and regulation of gene expression. Located in cytosol and nucleoplasm. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Jul 2025] |
| Immunogen | This antibody was raised against from part region of human TLE1 protein (UniProt: Q04724) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 7088 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈83.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 83.2 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q04724 |
| Note | Gene ID: 7088; UniProt: Q04724; Chromosome: 9q21.32; Predicted MW: 83.2 kDa |
| Function | Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity). The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TLE1 Polyclonal Antibody |
| Target | TLE1 |
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