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Rabbit Anti-TGIF2 Polyclonal Antibody
Rabbit Anti-TGIF2 Polyclonal Antibody

Rabbit Anti-TGIF2 Polyclonal Antibody

产品编号

PAV4012

别名

TGFB induced factor homeobox 2

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
AliasTGFB induced factor homeobox 2
Catalog NumberPAV4012
Product DescriptionRabbit polyclonal antibody raised against human TGIF2 (Homeobox protein TGIF2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameTGIF2
SpeciesHuman, Mouse
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family转录因子
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThe protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010]
ImmunogenThis antibody was raised against from part region of human TGIF2 protein (UniProt: Q9GZN2)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID60436
TagUnconjugated
Cross-reactivityHuman, Mouse
Predicted Molecular Weight≈25.9 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight25.9 kDa
Cross-reactivityHuman, Mouse
Uniprot IDQ9GZN2
NoteGene ID: 60436; UniProt: Q9GZN2; Chromosome: 20q11.23; Predicted MW: 25.9 kDa
FunctionTranscriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human TGIF2 Polyclonal Antibody
TargetTGIF2

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