Rabbit Anti-TBR1 Polyclonal Antibody
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产品编号
PAV3974
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别名
T-box brain transcription factor 1, AUTS5, IDDAS, TBR-1, TES-56
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | T-box brain transcription factor 1, AUTS5, IDDAS, TBR-1, TES-56 |
| Catalog Number | PAV3974 |
| Product Description | Rabbit polyclonal antibody raised against human TBR1 (T-box brain protein 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TBR1 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015] |
| Immunogen | This antibody was raised against from part region of human TBR1 protein (UniProt: Q16650) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 10716 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈74.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 74.1 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q16650 |
| Note | Gene ID: 10716; UniProt: Q16650; Chromosome: 2q24.2; Predicted MW: 74.1 kDa |
| Function | Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TBR1 Polyclonal Antibody |
| Target | TBR1 |
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