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Rabbit Anti-T2AG/GTF2A2 Polyclonal Antibody
Rabbit Anti-T2AG/GTF2A2 Polyclonal Antibody

Rabbit Anti-T2AG/GTF2A2 Polyclonal Antibody

产品编号

PAV3919

别名

general transcription factor IIA subunit 2, HsT18745, T18745, TF2A2, TFIIA, TFIIA-12, TFIIA-gamma, TFIIAS

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasgeneral transcription factor IIA subunit 2, HsT18745, T18745, TF2A2, TFIIA, TFIIA-12, TFIIA-gamma, TFIIAS
Catalog NumberPAV3919
Product DescriptionRabbit polyclonal antibody raised against human GTF2A2 (Transcription initiation factor IIA subunit 2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameGTF2A2
SpeciesHuman, Mouse, Rat
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family转录因子
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundAccurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).[supplied by OMIM, Mar 2008]
ImmunogenThis antibody was raised against from part region of human GTF2A2 protein (UniProt: P52657)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID2958
TagUnconjugated
Cross-reactivityHuman, Mouse, Rat
Predicted Molecular Weight≈12.5 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight12.5 kDa
Cross-reactivityHuman, Mouse, Rat
Uniprot IDP52657
NoteGene ID: 2958; UniProt: P52657; Chromosome: 15q22.2; Predicted MW: 12.5 kDa
FunctionTFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human GTF2A2 Polyclonal Antibody
TargetGTF2A2

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