Rabbit Anti-SOX3 Polyclonal Antibody
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产品编号
PAV3758
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别名
SRY-box transcription factor 3, GHDX, MRGH, PHP, PHPX, SOXB
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | SRY-box transcription factor 3, GHDX, MRGH, PHP, PHPX, SOXB |
| Catalog Number | PAV3758 |
| Product Description | Rabbit polyclonal antibody raised against human SOX3 (Transcription factor SOX-3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SOX3 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked cognitive disability with growth hormone deficiency. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human SOX3 protein (UniProt: P41225) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 6658 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈45.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 45.2 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | P41225 |
| Note | Gene ID: 6658; UniProt: P41225; Chromosome: Xq27.1; Predicted MW: 45.2 kDa |
| Function | Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SOX3 Polyclonal Antibody |
| Target | SOX3 |
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