Rabbit Anti-SOX10 Polyclonal Antibody

产品编号

PAV3754

别名

SRY-box transcription factor 10, DOM, PCWH, SOX-10, WS2E, WS4, WS4C

目录价格

InquiryRMB

规格

100ul

DATASHEET COA

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产品介绍

Alias	SRY-box transcription factor 10, DOM, PCWH, SOX-10, WS2E, WS4, WS4C
Catalog Number	PAV3754
Product Description	Rabbit polyclonal antibody raised against human SOX10 (Transcription factor SOX-10). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular Name	SOX10
Species	Human, Rat, Mouse
Host	Rabbit
Size	100ul
Clonity	Polyclonal
Protein Family	转录因子
Concentration	1 mg/ml
Purification	affinity-chromatography
Formulation	supply in PBS containing 50% glycerol, and 0.02% sodium azide.
Background	This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008]
Immunogen	This antibody was raised against from part region of human SOX10 protein (UniProt: P56693)
Application	WB, ELISA
Recommended Dilution	WB 1:500-2000 ELISA 1:5000-20000
Gene ID	6663
Tag	Unconjugated
Cross-reactivity	Human, Rat, Mouse
Predicted Molecular Weight	≈49.9 kDa
Storage Condition	Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping Condition	This product is shipped on blue ice.
Molecular Weight	49.9 kDa
Cross-reactivity	Human, Rat, Mouse
Uniprot ID	P56693
Note	Gene ID: 6663; UniProt: P56693; Chromosome: 22q13.1; Predicted MW: 49.9 kDa
Function	Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3. Transcriptional activator of MBP, via binding to the gene promoter (By similarity).
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human SOX10 Polyclonal Antibody
Target	SOX10