Rabbit Anti-RPF1/POU6F2 Polyclonal Antibody
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产品编号
PAV3457
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别名
POU class 6 homeobox 2, RPF-1, WT5, WTSL
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | POU class 6 homeobox 2, RPF-1, WT5, WTSL |
| Catalog Number | PAV3457 |
| Product Description | Rabbit polyclonal antibody raised against human POU6F2 (POU domain, class 6, transcription factor 2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | POU6F2 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Oct 2009] |
| Immunogen | This antibody was raised against from part region of human POU6F2 protein (UniProt: P78424) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 11281 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈73.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 73.3 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | P78424 |
| Note | Gene ID: 11281; UniProt: P78424; Chromosome: 7p14.1; Predicted MW: 73.3 kDa |
| Function | Probable transcription factor likely to be involved in early steps in the differentiation of amacrine and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'. Isoform 1 does not bind DNA. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human POU6F2 Polyclonal Antibody |
| Target | POU6F2 |
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