Rabbit Anti-PO3F2/POU3F2 Polyclonal Antibody
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产品编号
PAV3098
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别名
POU class 3 homeobox 2, BRN2, N-Oct3, OCT7, OTF-7, OTF7, POUF3, brn-2, oct-7
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | POU class 3 homeobox 2, BRN2, N-Oct3, OCT7, OTF-7, OTF7, POUF3, brn-2, oct-7 |
| Catalog Number | PAV3098 |
| Product Description | Rabbit polyclonal antibody raised against human POU3F2 (POU domain, class 3, transcription factor 2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | POU3F2 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells. [provided by RefSeq, Mar 2012] |
| Immunogen | This antibody was raised against from part region of human POU3F2 protein (UniProt: P20265) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 5454 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈46.9 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 46.9 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | P20265 |
| Note | Gene ID: 5454; UniProt: P20265; Chromosome: 6q16.1; Predicted MW: 46.9 kDa |
| Function | Transcription factor that plays a key role in neuronal differentiation (By similarity). Binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a non-conserved spacer region of 0, 2, or 3 nucleotides (By similarity). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters (By similarity). The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro (By similarity). Acts downstream of ASCL1, accessing chromatin that has been opened by ASCL1, and promotes transcription of neuronal genes (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human POU3F2 Polyclonal Antibody |
| Target | POU3F2 |
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