Rabbit Anti-PHX2B/PHOX2B Polyclonal Antibody
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产品编号
PAV3029
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别名
paired like homeobox 2B, CCHS, NBLST2, NBPhox, PMX2B
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | paired like homeobox 2B, CCHS, NBLST2, NBPhox, PMX2B |
| Catalog Number | PAV3029 |
| Product Description | Rabbit polyclonal antibody raised against human PHOX2B (Paired mesoderm homeobox protein 2B). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PHOX2B |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016] |
| Immunogen | This antibody was raised against from part region of human PHOX2B protein (UniProt: Q99453) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 8929 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈31.6 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 31.6 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q99453 |
| Note | Gene ID: 8929; UniProt: Q99453; Chromosome: 4p13; Predicted MW: 31.6 kDa |
| Function | Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PHOX2B Polyclonal Antibody |
| Target | PHOX2B |
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