Rabbit Anti-NKX62/NKX6-2 Polyclonal Antibody
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产品编号
PAV2539
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别名
NK6 homeobox 2, GTX, NKX6.2, NKX6B, SPAX8
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | NK6 homeobox 2, GTX, NKX6.2, NKX6B, SPAX8 |
| Catalog Number | PAV2539 |
| Product Description | Rabbit polyclonal antibody raised against human NKX6-2 (Homeobox protein Nkx-6.2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NKX6-2 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in cell differentiation; regulation of DNA-templated transcription; and regulation of myelination. Predicted to act upstream of or within several processes, including central nervous system myelination; negative regulation of transcription by RNA polymerase II; and regulation of gliogenesis. Predicted to be located in chromatin. Predicted to be active in nucleus. Implicated in spastic ataxia 8. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human NKX6-2 protein (UniProt: Q9C056) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 84504 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈29.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 29.3 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9C056 |
| Note | Gene ID: 84504; UniProt: Q9C056; Chromosome: 10q26.3; Predicted MW: 29.3 kDa |
| Function | Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'-(A/T)TTAATGA-3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NKX6-2 Polyclonal Antibody |
| Target | NKX6-2 |
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