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Rabbit Anti-NKAP Polyclonal Antibody
Rabbit Anti-NKAP Polyclonal Antibody

Rabbit Anti-NKAP Polyclonal Antibody

产品编号

PAV2533

别名

NFKB activating protein, MRXSHD

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
AliasNFKB activating protein, MRXSHD
Catalog NumberPAV2533
Product DescriptionRabbit polyclonal antibody raised against human NKAP (NF-kappa-B-activating protein). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameNKAP
SpeciesHuman
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family转录因子
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThis gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010]
ImmunogenThis antibody was raised against from part region of human NKAP protein (UniProt: Q8N5F7)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID79576
TagUnconjugated
Cross-reactivityHuman
Predicted Molecular Weight≈47.1 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight47.1 kDa
Cross-reactivityHuman
Uniprot IDQ8N5F7
NoteGene ID: 79576; UniProt: Q8N5F7; Chromosome: Xq24; Predicted MW: 47.1 kDa
FunctionActs as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development. Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human NKAP Polyclonal Antibody
TargetNKAP

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