Rabbit Anti-NCYM/MYCNOS Polyclonal Antibody
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产品编号
PAV2468
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别名
MYCN opposite strand, MYCN-AS1, N-CYM, NCYM, NYCM
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | MYCN opposite strand, MYCN-AS1, N-CYM, NCYM, NYCM |
| Catalog Number | PAV2468 |
| Product Description | Rabbit polyclonal antibody raised against human MYCNOS (N-cym protein). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MYCNOS |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene is transcribed in antisense to the v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog gene (MYCN). It is thought to encode a small, novel protein that stabilizes MYCN, prevents apoptosis, and promotes cell proliferation. Transcripts at this locus may also act directly as functional RNAs to recruit transcriptional regulators to the promoter of MYCN and stimulate transcription of this oncogene. This gene therefore functions through both RNA and protein products. [provided by RefSeq, Aug 2016] |
| Immunogen | This antibody was raised against from part region of human MYCNOS protein (UniProt: P40205) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 10408 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈11.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 11.7 kDa |
| Cross-reactivity | Human |
| Uniprot ID | P40205 |
| Note | Gene ID: 10408; UniProt: P40205; Chromosome: 2p24.3; Predicted MW: 11.7 kDa |
| Function | Regulates stability of MYCN in neuroblastoma cells by inhibiting GSK3B-mediated MYCN phosphorylation. Inhibits GSK3B activity by promoting its phosphorylation at 'Ser-9'. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MYCNOS Polyclonal Antibody |
| Target | MYCNOS |
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