Rabbit Anti-MKKS/MKKS Polyclonal Antibody
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产品编号
PAV2319
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别名
MKKS centrosomal shuttling protein, BBS6, HMCS, KMS, MKS
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | MKKS centrosomal shuttling protein, BBS6, HMCS, KMS, MKS |
| Catalog Number | PAV2319 |
| Product Description | Rabbit polyclonal antibody raised against human MKKS (Molecular chaperone MKKS). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MKKS |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2023] |
| Immunogen | This antibody was raised against from part region of human MKKS protein (UniProt: Q9NPJ1) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 8195 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈62.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 62.3 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9NPJ1 |
| Note | Gene ID: 8195; UniProt: Q9NPJ1; Chromosome: 20p12.2; Predicted MW: 62.3 kDa |
| Function | Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MKKS Polyclonal Antibody |
| Target | MKKS |
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