Rabbit Anti-U2AF1/U2AF1L4 Polyclonal Antibody
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产品编号
PAV4199
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别名
U2 small nuclear RNA auxiliary factor 1 like 4, U2AF1-RS3, U2AF1L3, U2AF1L3V1, U2AF1RS3, U2af26
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | U2 small nuclear RNA auxiliary factor 1 like 4, U2AF1-RS3, U2AF1L3, U2AF1L3V1, U2AF1RS3, U2af26 |
| Catalog Number | PAV4199 |
| Product Description | Rabbit polyclonal antibody raised against human U2AF1L4 (Splicing factor U2AF 26 kDa subunit small nuclear RNA auxiliary factor 1-like protein 3)). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | U2AF1L4 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Predicted to enable pre-mRNA 3'-splice site binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be part of U2AF complex and spliceosomal complex. [provided by Alliance of Genome Resources, Jul 2025] |
| Immunogen | This antibody was raised against from part region of human U2AF1L4 protein (UniProt: Q8WU68) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 199746 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈25.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 25.7 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q8WU68 |
| Note | Gene ID: 199746; UniProt: Q8WU68; Chromosome: 19q13.12; Predicted MW: 25.7 kDa |
| Function | RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human U2AF1L4 Polyclonal Antibody |
| Target | U2AF1L4 |
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