Rabbit Anti-TDRKH Polyclonal Antibody

产品编号

PAV3994

别名

tudor and KH domain containing, TDRD2

目录价格

InquiryRMB

规格

100ul

DATASHEET COA

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产品介绍

Alias	tudor and KH domain containing, TDRD2
Catalog Number	PAV3994
Product Description	Rabbit polyclonal antibody raised against human TDRKH (Tudor and KH domain-containing protein). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular Name	TDRKH
Species	Human, Mouse
Host	Rabbit
Size	100ul
Clonity	Polyclonal
Protein Family	转录与RNA加工
Concentration	1 mg/ml
Purification	affinity-chromatography
Formulation	supply in PBS containing 50% glycerol, and 0.02% sodium azide.
Background	Predicted to enable RNA binding activity. Predicted to be involved in several processes, including P granule organization; male meiotic nuclear division; and piRNA processing. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
Immunogen	This antibody was raised against from part region of human TDRKH protein (UniProt: Q9Y2W6)
Application	WB
Recommended Dilution	WB 1:500-2000
Gene ID	11022
Tag	Unconjugated
Cross-reactivity	Human, Mouse
Predicted Molecular Weight	≈62.0 kDa
Storage Condition	Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping Condition	This product is shipped on blue ice.
Molecular Weight	62.0 kDa
Cross-reactivity	Human, Mouse
Uniprot ID	Q9Y2W6
Note	Gene ID: 11022; UniProt: Q9Y2W6; Chromosome: 1q21.3; Predicted MW: 62.0 kDa
Function	Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human TDRKH Polyclonal Antibody
Target	TDRKH