Rabbit Anti-TAF4B Polyclonal Antibody
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产品编号
PAV3947
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别名
TATA-box binding protein associated factor 4b, SPGF13, TAF2C2, TAFII105
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | TATA-box binding protein associated factor 4b, SPGF13, TAF2C2, TAFII105 |
| Catalog Number | PAV3947 |
| Product Description | Rabbit polyclonal antibody raised against human TAF4B (Transcription initiation factor TFIID subunit 4B105)). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TAF4B |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | TATA binding protein (TBP) and TBP-associated factors (TAFs) participate in the formation of the TFIID protein complex, which is involved in initiation of transcription of genes by RNA polymerase II. This gene encodes a cell type-specific TAF that may be responsible for mediating transcription by a subset of activators in B cells. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] |
| Immunogen | This antibody was raised against from part region of human TAF4B protein (UniProt: Q92750) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 6875 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈91.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 91.1 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q92750 |
| Note | Gene ID: 6875; UniProt: Q92750; Chromosome: 18q11.2; Predicted MW: 91.1 kDa |
| Function | Cell type-specific subunit of the general transcription factor TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAF4B is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Plays a role in spermiogenesis and oogenesis. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TAF4B Polyclonal Antibody |
| Target | TAF4B |
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