Rabbit Anti-TAF1B Polyclonal Antibody
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产品编号
PAV3944
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别名
TATA-box binding protein associated factor, RNA polymerase I subunit B, MGC:9349, RAF1B, RAFI63, SL1, TAFI63
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | TATA-box binding protein associated factor, RNA polymerase I subunit B, MGC:9349, RAF1B, RAFI63, SL1, TAFI63 |
| Catalog Number | PAV3944 |
| Product Description | Rabbit polyclonal antibody raised against human TAF1B (TATA box-binding protein-associated factor RNA polymerase I subunit B). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TAF1B |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] |
| Immunogen | This antibody was raised against from part region of human TAF1B protein (UniProt: Q53T94) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 9014 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈68.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 68.8 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q53T94 |
| Note | Gene ID: 9014; UniProt: Q53T94; Chromosome: 2p25.1; Predicted MW: 68.8 kDa |
| Function | Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TAF1B Polyclonal Antibody |
| Target | TAF1B |
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