Rabbit Anti-SPT16/SUPT16H Polyclonal Antibody
-
产品编号
PAV3801
-
别名
SPT16 homolog, facilitates chromatin remodeling subunit, CDC68, FACTP140, NEDDFAC, SPT16, SPT16/CDC68
-
目录价格
InquiryRMB
-
规格
- 100ul
产品介绍
| Alias | SPT16 homolog, facilitates chromatin remodeling subunit, CDC68, FACTP140, NEDDFAC, SPT16, SPT16/CDC68 |
| Catalog Number | PAV3801 |
| Product Description | Rabbit polyclonal antibody raised against human SUPT16H (FACT complex subunit SPT16). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SUPT16H |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009] |
| Immunogen | This antibody was raised against from part region of human SUPT16H protein (UniProt: Q9Y5B9) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 11198 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈119.9 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 119.9 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9Y5B9 |
| Note | Gene ID: 11198; UniProt: Q9Y5B9; Chromosome: 14q11.2; Predicted MW: 119.9 kDa |
| Function | Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SUPT16H Polyclonal Antibody |
| Target | SUPT16H |
- 联系我们
- 电话：400-621-6806
- 手机：13116038708（微信）
- 邮箱：info@kmdbioscience.com
- 地址：天津市武清开发区和畅路6号10号厂房108室
-
销售微信
-
官方公众号
-
400-621-6806 -
3599163699 -
周一至周五 9:00-18:00 -
-
0
-
