Rabbit Anti-SPF45/RBM17 Polyclonal Antibody
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产品编号
PAV3785
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别名
RNA binding motif protein 17, SPF45
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | RNA binding motif protein 17, SPF45 |
| Catalog Number | PAV3785 |
| Product Description | Rabbit polyclonal antibody raised against human RBM17 (Splicing factor 45). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RBM17 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009] |
| Immunogen | This antibody was raised against from part region of human RBM17 protein (UniProt: Q96I25) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 84991 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈45.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 45.0 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q96I25 |
| Note | Gene ID: 84991; UniProt: Q96I25; Chromosome: 10p15.1; Predicted MW: 45.0 kDa |
| Function | Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RBM17 Polyclonal Antibody |
| Target | RBM17 |
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