Rabbit Anti-SNUT1/SART1 Polyclonal Antibody
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产品编号
PAV3736
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别名
spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP, Ara1, HAF, HOMS1, SART1259, SNRNP110, Snu66
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP, Ara1, HAF, HOMS1, SART1259, SNRNP110, Snu66 |
| Catalog Number | PAV3736 |
| Product Description | Rabbit polyclonal antibody raised against human SART1 (U4/U6.U5 tri-snRNP-associated protein 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SART1 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human SART1 protein (UniProt: O43290) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 9092 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈90.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 90.3 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | O43290 |
| Note | Gene ID: 9092; UniProt: O43290; Chromosome: 11q13.1; Predicted MW: 90.3 kDa |
| Function | Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SART1 Polyclonal Antibody |
| Target | SART1 |
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