Rabbit Anti-SMG9 Polyclonal Antibody
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产品编号
PAV3724
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别名
SMG9 nonsense mediated mRNA decay factor, C19orf61, F17127_1, HBMS, NEDITPO
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | SMG9 nonsense mediated mRNA decay factor, C19orf61, F17127_1, HBMS, NEDITPO |
| Catalog Number | PAV3724 |
| Product Description | Rabbit polyclonal antibody raised against human SMG9 (Nonsense-mediated mRNA decay factor SMG9). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SMG9 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录与RNA加工 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense-mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features. [provided by RefSeq, Jul 2016] |
| Immunogen | This antibody was raised against from part region of human SMG9 protein (UniProt: Q9H0W8) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 56006 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈57.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 57.7 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q9H0W8 |
| Note | Gene ID: 56006; UniProt: Q9H0W8; Chromosome: 19q13.31; Predicted MW: 57.7 kDa |
| Function | Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8. Plays a role in brain, heart, and eye development (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SMG9 Polyclonal Antibody |
| Target | SMG9 |
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